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15-oxoeicosatetraenoic acid mediates monocyte adhesion to endothelial cell

BACKGROUND: A great number of studies reported that 12/15-lipoxygenase (12/15-LO) played an important role in atherosclerosis. And its arachidonic acid(AA) metabolite, 15(S)-hydroperoxy-5,8,11,13-(Z,Z,Z,E)-eicosatetraenoic acid (15(S)-HETE), is demonstrated to mediate endothelial dysfunction. 15-oxo...

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Detalles Bibliográficos
Autores principales: Ma, Guohua, Pan, Bing, Ren, Sufen, Guo, Caixia, Guo, Yansong, Wei, Lixin, Zheng, Lemin, Chen, Buxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508789/
https://www.ncbi.nlm.nih.gov/pubmed/28701173
http://dx.doi.org/10.1186/s12944-017-0518-2