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A Recombinant 47-kDa Outer Membrane Protein Induces an Immune Response against Orientia tsutsugamushi Strain Boryong

We investigated the 47-kDa outer membrane protein (OMP), which is a periplasmic serine protease and an antigenic major surface protein of Orientia tsutsugamushi, as a vaccine candidate. We developed a conventional subunit vaccine expressing recombinant 47-kDa OMP (rec47) and a DNA vaccine (p47). In...

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Detalles Bibliográficos
Autores principales: Choi, Sangho, Jeong, Hang Jin, Hwang, Kyu-Jam, Gill, Byoungchul, Ju, Young Ran, Lee, Yeong Seon, Lee, Jeongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508880/
https://www.ncbi.nlm.nih.gov/pubmed/28719308
http://dx.doi.org/10.4269/ajtmh.15-0771