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Glutamyl Endopeptidases: The Puzzle of Substrate Specificity

Glutamyl endopeptidases (GEPases) are chymotrypsin-like enzymes that preferentially cleave the peptide bonds of the α-carboxyl groups of glutamic acid. Despite the many years of research, the structural determinants underlying the strong substrate specificity of GEPases still remain unclear. In this...

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Detalles Bibliográficos
Autores principales: Demidyuk, I.V., Chukhontseva, K.N., Kostrov, S.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508998/
https://www.ncbi.nlm.nih.gov/pubmed/28740724