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Huntington’s Disease: Calcium Dyshomeostasis and Pathology Models

Huntington’s disease (HD) is a severe inherited neurodegenerative disorder characterized by motor dysfunction, cognitive decline, and mental impairment. At the molecular level, HD is caused by a mutation in the first exon of the gene encoding the huntingtin protein. The mutation results in an expand...

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Detalles Bibliográficos
Autores principales: Kolobkova, Y.A., Vigont, V.A., Shalygin, A.V., Kaznacheyeva, E.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508999/
https://www.ncbi.nlm.nih.gov/pubmed/28740725