Differential chromatin profiles partially determine transcription factor binding

We characterize how genomic variants that alter chromatin accessibility influence regulatory factor binding with a new method called DeltaBind that predicts condition specific factor binding more accurately than other methods based on DNase-seq data. Using DeltaBind and DNase-seq experiments we pred...

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Detalles Bibliográficos
Autores principales: Chen, Rujian, Gifford, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509100/
https://www.ncbi.nlm.nih.gov/pubmed/28704389
http://dx.doi.org/10.1371/journal.pone.0179411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509100/
https://www.ncbi.nlm.nih.gov/pubmed/28704389
http://dx.doi.org/10.1371/journal.pone.0179411

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