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Differential chromatin profiles partially determine transcription factor binding
We characterize how genomic variants that alter chromatin accessibility influence regulatory factor binding with a new method called DeltaBind that predicts condition specific factor binding more accurately than other methods based on DNase-seq data. Using DeltaBind and DNase-seq experiments we pred...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509100/ https://www.ncbi.nlm.nih.gov/pubmed/28704389 http://dx.doi.org/10.1371/journal.pone.0179411 |