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Redifferentiation of aged human articular chondrocytes by combining bone morphogenetic protein-2 and melanoma inhibitory activity protein in 3D-culture

Melanoma inhibitory activity (MIA) affects the differentiation to hyaline cartilage and can inhibit the osteogenic potential of bone morphogenetic protein (BMP)-2 in mesenchymal stem cells (MSC). The aim of this study was to investigate if MIA also inhibits the osteogenic potential of BMP-2 in human...

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Detalles Bibliográficos
Autores principales: Payr, Stephan, Tichy, Brigitte, Atteneder, Clemens, Michel, Marc, Tiefenboeck, Thomas, Lang, Nikolaus, Nuernberger, Sylvia, Hajdu, Stefan, Rosado-Balmayor, Elizabeth, Marlovits, Stefan, Albrecht, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509113/
https://www.ncbi.nlm.nih.gov/pubmed/28704392
http://dx.doi.org/10.1371/journal.pone.0179729