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Dynamic changes in Bach1 expression in the kidney of rhabdomyolysis-associated acute kidney injury

Free heme, a pro-oxidant released from myoglobin, is thought to contribute to the pathogenesis of rhabdomyolysis-associated acute kidney injury (RM-AKI), because renal overexpression of heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme catabolism, confers protection against RM-AKI. BTB and C...

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Detalles Bibliográficos
Autores principales: Yamaoka, Masakazu, Shimizu, Hiroko, Takahashi, Toru, Omori, Emiko, Morimatsu, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509282/
https://www.ncbi.nlm.nih.gov/pubmed/28704479
http://dx.doi.org/10.1371/journal.pone.0180934