Spindle assembly checkpoint signaling and sister chromatid cohesion are disrupted by HPV E6-mediated transformation

Aneuploidy, a condition that results from unequal partitioning of chromosomes during mitosis, is a hallmark of many cancers, including those caused by human papillomaviruses (HPVs). E6 and E7 are the primary transforming proteins in HPV that drive tumor progression. In this study, we stably expresse...

Descripción completa

Detalles Bibliográficos
Autores principales: Shirnekhi, Hazheen K., Kelley, Erin P., DeLuca, Jennifer G., Herman, Jacob A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509418/
https://www.ncbi.nlm.nih.gov/pubmed/28539402
http://dx.doi.org/10.1091/mbc.E16-12-0853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509418/
https://www.ncbi.nlm.nih.gov/pubmed/28539402
http://dx.doi.org/10.1091/mbc.E16-12-0853

Ejemplares similares