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Spindle assembly checkpoint signaling and sister chromatid cohesion are disrupted by HPV E6-mediated transformation
Aneuploidy, a condition that results from unequal partitioning of chromosomes during mitosis, is a hallmark of many cancers, including those caused by human papillomaviruses (HPVs). E6 and E7 are the primary transforming proteins in HPV that drive tumor progression. In this study, we stably expresse...
Autores principales: | Shirnekhi, Hazheen K., Kelley, Erin P., DeLuca, Jennifer G., Herman, Jacob A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509418/ https://www.ncbi.nlm.nih.gov/pubmed/28539402 http://dx.doi.org/10.1091/mbc.E16-12-0853 |
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