Leishmania donovani restricts mitochondrial dynamics to enhance miRNP stability and target RNA repression in host macrophages

MicroRNAs (miRNAs), the tiny regulatory RNAs, form complexes with Argonaute (Ago) proteins and inhibit gene expression in metazoan cells. While studying parasite-invaded macrophages, we identify a unique mode of gene regulation in which the parasite Leishmania donovani (Ld) causes mitochondrial depo...

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Detalles Bibliográficos
Autores principales: Chakrabarty, Yogaditya, Bhattacharyya, Suvendra N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509422/
https://www.ncbi.nlm.nih.gov/pubmed/28539410
http://dx.doi.org/10.1091/mbc.E16-06-0388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509422/
https://www.ncbi.nlm.nih.gov/pubmed/28539410
http://dx.doi.org/10.1091/mbc.E16-06-0388

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