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NEK7 is required for G1 progression and procentriole formation

The decision to commit to the cell cycle is made during G1 through the concerted action of various cyclin–CDK complexes. Not only DNA replication, but also centriole duplication is initiated as cells enter the S-phase. The NIMA-related kinase NEK7 is one of many factors required for proper centriole...

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Detalles Bibliográficos
Autores principales: Gupta, Akshari, Tsuchiya, Yuki, Ohta, Midori, Shiratsuchi, Gen, Kitagawa, Daiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509424/
https://www.ncbi.nlm.nih.gov/pubmed/28539406
http://dx.doi.org/10.1091/mbc.E16-09-0643