Spatial analysis of Cdc42 activity reveals a role for plasma membrane–associated Cdc42 in centrosome regulation

The ability of the small GTPase Cdc42 to regulate diverse cellular processes depends on tight spatial control of its activity. Cdc42 function is best understood at the plasma membrane (PM), where it regulates cytoskeletal organization and cell polarization. Active Cdc42 has also been detected at the...

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Detalles Bibliográficos
Autores principales: Herrington, Kari A., Trinh, Andrew L., Dang, Carolyn, O’Shaughnessy, Ellen, Hahn, Klaus M., Gratton, Enrico, Digman, Michelle A., Sütterlin, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509425/
https://www.ncbi.nlm.nih.gov/pubmed/28539409
http://dx.doi.org/10.1091/mbc.E16-09-0665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509425/
https://www.ncbi.nlm.nih.gov/pubmed/28539409
http://dx.doi.org/10.1091/mbc.E16-09-0665

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