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Spatial analysis of Cdc42 activity reveals a role for plasma membrane–associated Cdc42 in centrosome regulation
The ability of the small GTPase Cdc42 to regulate diverse cellular processes depends on tight spatial control of its activity. Cdc42 function is best understood at the plasma membrane (PM), where it regulates cytoskeletal organization and cell polarization. Active Cdc42 has also been detected at the...
Autores principales: | Herrington, Kari A., Trinh, Andrew L., Dang, Carolyn, O’Shaughnessy, Ellen, Hahn, Klaus M., Gratton, Enrico, Digman, Michelle A., Sütterlin, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509425/ https://www.ncbi.nlm.nih.gov/pubmed/28539409 http://dx.doi.org/10.1091/mbc.E16-09-0665 |
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