SEC23B is required for pancreatic acinar cell function in adult mice

Mice with germline absence of SEC23B die perinatally, exhibiting massive pancreatic degeneration. We generated mice with tamoxifen-inducible, pancreatic acinar cell–specific Sec23b deletion. Inactivation of Sec23b exclusively in the pancreatic acinar cells of adult mice results in decreased overall...

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Detalles Bibliográficos
Autores principales: Khoriaty, Rami, Vogel, Nancy, Hoenerhoff, Mark J., Sans, M. Dolors, Zhu, Guojing, Everett, Lesley, Nelson, Bradley, Durairaj, Haritha, McKnight, Brooke, Zhang, Bin, Ernst, Stephen A., Ginsburg, David, Williams, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509426/
https://www.ncbi.nlm.nih.gov/pubmed/28539403
http://dx.doi.org/10.1091/mbc.E17-01-0001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509426/
https://www.ncbi.nlm.nih.gov/pubmed/28539403
http://dx.doi.org/10.1091/mbc.E17-01-0001

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