Cargando…

SEC23B is required for pancreatic acinar cell function in adult mice

Mice with germline absence of SEC23B die perinatally, exhibiting massive pancreatic degeneration. We generated mice with tamoxifen-inducible, pancreatic acinar cell–specific Sec23b deletion. Inactivation of Sec23b exclusively in the pancreatic acinar cells of adult mice results in decreased overall...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khoriaty, Rami, Vogel, Nancy, Hoenerhoff, Mark J., Sans, M. Dolors, Zhu, Guojing, Everett, Lesley, Nelson, Bradley, Durairaj, Haritha, McKnight, Brooke, Zhang, Bin, Ernst, Stephen A., Ginsburg, David, Williams, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509426/ https://www.ncbi.nlm.nih.gov/pubmed/28539403 http://dx.doi.org/10.1091/mbc.E17-01-0001

Ejemplares similares

Pancreatic SEC23B deficiency is sufficient to explain the perinatal lethality of germline SEC23B deficiency in mice
por: Khoriaty, Rami, et al.
Publicado: (2016)

Murine SEC24D can substitute functionally for SEC24C during embryonic development
por: Adams, Elizabeth J., et al.
Publicado: (2021)

SNARE protein SEC22B regulates early embryonic development
por: Wu, Shin-Rong J., et al.
Publicado: (2019)

SEC23A rescues SEC23B-deficient congenital dyserythropoietic anemia type II
por: King, Richard, et al.
Publicado: (2021)

Neural tube opening and abnormal extraembryonic membrane development in SEC23A deficient mice
por: Zhu, Min, et al.
Publicado: (2015)

A common human missense mutation of vesicle coat protein SEC23B leads to growth restriction and chronic pancreatitis in mice
por: Wei, Wei, et al.
Publicado: (2021)

Insulin protects acinar cells during pancreatitis by preserving glycolytic ATP supply to calcium pumps
por: Bruce, Jason I. E., et al.
Publicado: (2021)

The Arabidopsis COPII components, AtSEC23A and AtSEC23D, are essential for pollen wall development and exine patterning
por: Aboulela, Mostafa, et al.
Publicado: (2018)

ALG-2 Attenuates COPII Budding In Vitro and Stabilizes the Sec23/Sec31A Complex
por: la Cour, Jonas M., et al.
Publicado: (2013)

Sar1 Interacts with Sec23/Sec24 and Sec13/Sec31 Complexes: Insight into Its Involvement in the Assembly of Coat Protein Complex II in the Microsporidian Nosema bombycis
por: Sun, Fuzhen, et al.
Publicado: (2022)

Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23p
Publicado: (1995)

SEC23A confers ER stress resistance in gastric cancer by forming the ER stress-SEC23A-autophagy negative feedback loop
por: Cheng, Quan, et al.
Publicado: (2023)

Sequential interactions with Sec23 control the direction of vesicle traffic
por: Lord, Christopher, et al.
Publicado: (2011)

The Functional Role of SEC23 in Vesicle Transportation, Autophagy and Cancer
por: Jing, Jingchen, et al.
Publicado: (2019)

The 12 Item Social and Economic Conservatism Scale (SECS)
por: Everett, Jim A. C.
Publicado: (2013)

Smy2p Participates in COPII Vesicle Formation Through the Interaction with Sec23p/Sec24p Subcomplex
por: Higashio, Hironori, et al.
Publicado: (2008)

Murine Surf4 is essential for early embryonic development
por: Emmer, Brian T., et al.
Publicado: (2020)

Disruption of the Sec24d Gene Results in Early Embryonic Lethality in the Mouse
por: Baines, Andrea C., et al.
Publicado: (2013)

MicroRNA-375/SEC23A as biomarkers of the in vitro efficacy of vandetanib
por: Lassalle, Sandra, et al.
Publicado: (2016)

The ULK1-FBXW5-SEC23B nexus controls autophagy
por: Jeong, Yeon-Tae, et al.
Publicado: (2018)

Particle dynamics and deposition in true-scale pulmonary acinar models
por: Fishler, Rami, et al.
Publicado: (2015)

Let’s talk about Secs: Sec61, Sec62 and Sec63 in signal transduction, oncology and personalized medicine
por: Linxweiler, Maximilian, et al.
Publicado: (2017)

Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62
por: Itskanov, Samuel, et al.
Publicado: (2021)

Acinar Cell Cystadenoma (Acinar Cystic Transformation) of the Pancreas: the Radiologic-Pathologic Features
por: Gumus, Mehmet, et al.
Publicado: (2011)

SEC23A Is an Independent Prognostic Biomarker in Bladder Cancer Correlated With MAPK Signaling
por: Zeng, Bin, et al.
Publicado: (2021)

Maintenance of Acinar Cell Organization is Critical to Preventing Kras-Induced Acinar-Ductal Metaplasia
por: Shi, Guanglu, et al.
Publicado: (2012)

TGF-β1 promotes acinar to ductal metaplasia of human pancreatic acinar cells
por: Liu, Jun, et al.
Publicado: (2016)

Dietary Protein and Amino Acid Deficiency Inhibit Pancreatic Digestive Enzyme mRNA Translation by Multiple Mechanisms
por: Sans, Maria Dolors, et al.
Publicado: (2020)

CREB3L2-mediated expression of Sec23A/Sec24D is involved in hepatic stellate cell activation through ER-Golgi transport
por: Tomoishi, Shotaro, et al.
Publicado: (2017)

Congenital Dyserythropoietic Anemia Type II: molecular analysis and expression of the SEC23B Gene
por: Punzo, Francesca, et al.
Publicado: (2011)

Non-canonical role of cancer-associated mutant SEC23B in the ribosome biogenesis pathway
por: Yehia, Lamis, et al.
Publicado: (2018)

Sec23a mediates miR-200c augmented oligometastatic to polymetastatic progression
por: Sun, Zhiwei, et al.
Publicado: (2018)

Mutations in the coat complex II component SEC23B promote colorectal cancer metastasis
por: Yang, Chunyuan, et al.
Publicado: (2020)

Non-canonical role of wild-type SEC23B in the cellular stress response pathway
por: Yehia, Lamis, et al.
Publicado: (2021)

miR-1227 Targets SEC23A to Regulate the Shedding of Large Extracellular Vesicles
por: Chin, Andrew, et al.
Publicado: (2021)

Increased SEC23A Expression Correlates with Poor Prognosis and Immune Infiltration in Stomach Adenocarcinoma †
por: Zhaoran, Su, et al.
Publicado: (2023)

Acinar Cell Cystadenocarcinoma of the Pancreas
por: Aoto, Keita, et al.
Publicado: (2017)

Pancreatic Acinar Cell Carcinoma
por: Béchade, Dominique, et al.
Publicado: (2016)

SEC Reporting
por: USA, BDO
Publicado: (2020)

Pancreatic acinar cell carcinoma: A review on molecular profiling of patient tumors
por: Al-Hader, Ahmad, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_8g4u7asr2donouarn0iuul9lq7