ABCB1 Genotype is Associated with Fentanyl Requirements in Critically Ill Children

BACKGROUND: The gene ABCB1 encodes p-glycoprotein, a xenobiotic efflux pump capable of transporting certain opioids, including fentanyl. ABCB1 genotype has been previously associated with patient opioid requirements and may influence fentanyl dosing requirements in critically ill children. METHODS:...

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Detalles Bibliográficos
Autores principales: Horvat, Christopher M., Au, Alicia K., Conley, Yvette L., Kochanek, Patrick M., Li, Lingjue, Poloyac, Samuel L., Empey, Philip E., Clark, Robert S. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509475/
https://www.ncbi.nlm.nih.gov/pubmed/28388599
http://dx.doi.org/10.1038/pr.2017.103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509475/
https://www.ncbi.nlm.nih.gov/pubmed/28388599
http://dx.doi.org/10.1038/pr.2017.103

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