Cargando…

MUC1-C INTEGRATES PD-L1 INDUCTION WITH REPRESSION OF IMMUNE EFFECTORS IN NON-SMALL CELL LUNG CANCER

Immunotherapeutic approaches, particularly PD-1/PD-L1 blockade, have improved the treatment of non-small cell lung cancer (NSCLC), supporting the premise that evasion of immune destruction is of importance for NSCLC progression. However, the signals responsible for upregulation of PD-L1 in NSCLC cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Bouillez, Audrey, Rajabi, Hasan, Jin, Caining, Samur, Mehmet, Tagde, Ashujit, Alam, Maroof, Hiraki, Masayuki, Maeda, Takahiro, Hu, Xiufeng, Adeegbe, Dennis, Kharbanda, Surender, Wong, Kwok-Kin, Kufe, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509481/
https://www.ncbi.nlm.nih.gov/pubmed/28288138
http://dx.doi.org/10.1038/onc.2017.47