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Early post-natal exposure to intermittent hypoxia in rodents is pro-inflammatory, impairs white matter integrity and alters brain metabolism

BACKGROUND: Preterm infants are frequently exposed to intermittent hypoxia (IH) associated with apnea and periodic breathing that may result in inflammation and brain injury that later manifests as cognitive and executive function deficits. We used a rodent model to determine whether early postnatal...

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Detalles Bibliográficos
Autores principales: Darnall, Robert A., Chen, Xi, Nemani, Krishnamurthy V., Sirieix, Chrystelle M., Gimi, Barjor, Knoblach, Susan, McEntire, Betty L., Hunt, Carl E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509485/
https://www.ncbi.nlm.nih.gov/pubmed/28388601
http://dx.doi.org/10.1038/pr.2017.102