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A Haystack Heuristic for Autoimmune Disease Biomarker Discovery Using Next-Gen Immune Repertoire Sequencing Data

Large-scale DNA sequencing of immunological repertoires offers an opportunity for the discovery of novel biomarkers for autoimmune disease. Available bioinformatics techniques however, are not adequately suited for elucidating possible biomarker candidates from within large immunosequencing datasets...

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Detalles Bibliográficos
Autores principales: Apeltsin, Leonard, Wang, Shengzhi, von Büdingen, H.-Christian, Sirota, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509648/
https://www.ncbi.nlm.nih.gov/pubmed/28706301
http://dx.doi.org/10.1038/s41598-017-04439-5