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A Haystack Heuristic for Autoimmune Disease Biomarker Discovery Using Next-Gen Immune Repertoire Sequencing Data
Large-scale DNA sequencing of immunological repertoires offers an opportunity for the discovery of novel biomarkers for autoimmune disease. Available bioinformatics techniques however, are not adequately suited for elucidating possible biomarker candidates from within large immunosequencing datasets...
Autores principales: | Apeltsin, Leonard, Wang, Shengzhi, von Büdingen, H.-Christian, Sirota, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509648/ https://www.ncbi.nlm.nih.gov/pubmed/28706301 http://dx.doi.org/10.1038/s41598-017-04439-5 |
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