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PLAG1 deficiency impairs spermatogenesis and sperm motility in mice

Deficiency in pleomorphic adenoma gene 1 (PLAG1) leads to reduced fertility in male mice, but the mechanism by which PLAG1 contributes to reproduction is unknown. To investigate the involvement of PLAG1 in testicular function, we determined (i) the spatial distribution of PLAG1 in the testis using X...

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Detalles Bibliográficos
Autores principales: Juma, Almas R., Grommen, Sylvia V. H., O’Bryan, Moira K., O’Connor, Anne E., Merriner, D. Jo, Hall, Nathan E., Doyle, Stephen R., Damdimopoulou, Pauliina E., Barriga, Daniel, Hart, Adam H., Van de Ven, Wim J. M., De Groef, Bert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509656/
https://www.ncbi.nlm.nih.gov/pubmed/28706261
http://dx.doi.org/10.1038/s41598-017-05676-4