Suppressed autophagic response underlies augmentation of renal ischemia/reperfusion injury by type 2 diabetes

Diabetes mellitus is a major risk factor for acute kidney injury (AKI). Here, we hypothesized that suppression of autophagic response underlies aggravation of renal ischemia/reperfusion (I/R) injury by type 2 diabetes mellitus (T2DM). In OLETF, a rat model of T2DM, and its non-diabetic control, LETO...

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Detalles Bibliográficos
Autores principales: Muratsubaki, Shingo, Kuno, Atsushi, Tanno, Masaya, Miki, Takayuki, Yano, Toshiyuki, Sugawara, Hirohito, Shibata, Satoru, Abe, Koki, Ishikawa, Satoko, Ohno, Kouhei, Kimura, Yukishige, Tatekoshi, Yuki, Nakata, Kei, Ohwada, Wataru, Mizuno, Masashi, Miura, Tetsuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509657/
https://www.ncbi.nlm.nih.gov/pubmed/28706237
http://dx.doi.org/10.1038/s41598-017-05667-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509657/
https://www.ncbi.nlm.nih.gov/pubmed/28706237
http://dx.doi.org/10.1038/s41598-017-05667-5

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