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Connexin 50 Functions as an Adhesive Molecule and Promotes Lens Cell Differentiation

Connexins play essential roles in lens homeostasis and development. Here, we identified a new role for Cx50 that mediates cell-cell adhesion function. Cx50 enhanced the adhesive capability of AQP0. Interestingly, the expression of Cx50 alone promoted cell adhesion at a comparable level to AQP0; howe...

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Detalles Bibliográficos
Autores principales: Hu, Zhengping, Shi, Wen, Riquelme, Manuel A., Shi, Qian, Biswas, Sondip, Lo, Woo-Kuen, White, Thomas W., Gu, Sumin, Jiang, Jean X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509658/
https://www.ncbi.nlm.nih.gov/pubmed/28706245
http://dx.doi.org/10.1038/s41598-017-05647-9