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Genotypic variability based association identifies novel non-additive loci DHCR7 and IRF4 in sero-negative rheumatoid arthritis

Sero-negative rheumatoid arthritis (RA) is a highly heterogeneous disorder with only a few additive loci identified to date. We report a genotypic variability-based genome-wide association study (vGWAS) of six cohorts of sero-negative RA recruited in Europe and the US that were genotyped with the Im...

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Detalles Bibliográficos
Autores principales: Wei, Wen-Hua, Viatte, Sebastien, Merriman, Tony R., Barton, Anne, Worthington, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509675/
https://www.ncbi.nlm.nih.gov/pubmed/28706201
http://dx.doi.org/10.1038/s41598-017-05447-1