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Modeling Atrial Fibrillation using Human Embryonic Stem Cell-Derived Atrial Tissue

Since current experimental models of Atrial Fibrillation (AF) have significant limitations, we used human embryonic stem cells (hESCs) to generate an atrial-specific tissue model of AF for pharmacologic testing. We generated atrial-like cardiomyocytes (CMs) from hESCs which preferentially expressed...

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Detalles Bibliográficos
Autores principales: Laksman, Zachary, Wauchop, Marianne, Lin, Eric, Protze, Stephanie, Lee, Jeehoon, Yang, Wallace, Izaddoustdar, Farzad, Shafaattalab, Sanam, Gepstein, Lior, Tibbits, Glen F., Keller, Gordon, Backx, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509676/
https://www.ncbi.nlm.nih.gov/pubmed/28706272
http://dx.doi.org/10.1038/s41598-017-05652-y