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Modeling Atrial Fibrillation using Human Embryonic Stem Cell-Derived Atrial Tissue
Since current experimental models of Atrial Fibrillation (AF) have significant limitations, we used human embryonic stem cells (hESCs) to generate an atrial-specific tissue model of AF for pharmacologic testing. We generated atrial-like cardiomyocytes (CMs) from hESCs which preferentially expressed...
Autores principales: | Laksman, Zachary, Wauchop, Marianne, Lin, Eric, Protze, Stephanie, Lee, Jeehoon, Yang, Wallace, Izaddoustdar, Farzad, Shafaattalab, Sanam, Gepstein, Lior, Tibbits, Glen F., Keller, Gordon, Backx, Peter H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509676/ https://www.ncbi.nlm.nih.gov/pubmed/28706272 http://dx.doi.org/10.1038/s41598-017-05652-y |
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