Modulation of Interleukin-12 activity in the presence of heparin

Glycosaminoglycans (GAGs), especially heparin and heparan sulfate (HS), modulate the functions of numerous cytokines. The aims of this multidisciplinary research were to characterize heparin binding to interleukin-12 (IL-12) and determine the mechanism(s) by which heparin influences IL-12 bioactivit...

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Detalles Bibliográficos
Autores principales: Jayanthi, Srinivas, Koppolu, Bhanu prasanth, Nguyen, Khue G., Smith, Sean G., Felber, Barbara K., Kumar, Thallapuranam Krishnaswamy Suresh, Zaharoff, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509706/
https://www.ncbi.nlm.nih.gov/pubmed/28706183
http://dx.doi.org/10.1038/s41598-017-05382-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509706/
https://www.ncbi.nlm.nih.gov/pubmed/28706183
http://dx.doi.org/10.1038/s41598-017-05382-1

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