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Patch clamp-assisted single neuron lipidomics

Our understanding of the physiological and pathological functions of brain lipids is limited by the inability to analyze these molecules at cellular resolution. Here, we present a method that enables the detection of lipids in identified single neurons from live mammalian brains. Neuronal cell bodie...

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Detalles Bibliográficos
Autores principales: Merrill, Collin B., Basit, Abdul, Armirotti, Andrea, Jia, Yousheng, Gall, Christine M., Lynch, Gary, Piomelli, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509708/
https://www.ncbi.nlm.nih.gov/pubmed/28706218
http://dx.doi.org/10.1038/s41598-017-05607-3