A Simple Add-and-Display Method for Immobilisation of Cancer Drug on His-tagged Virus-like Nanoparticles for Controlled Drug Delivery

pH-responsive virus-like nanoparticles (VLNPs) hold promising potential as drug delivery systems for cancer therapy. In the present study, hepatitis B virus (HBV) VLNPs harbouring His-tags were used to display doxorubicin (DOX) via nitrilotriacetic acid (NTA) conjugation. The His-tags served as pH-r...

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Detalles Bibliográficos
Autores principales: Biabanikhankahdani, Roya, Bayat, Saadi, Ho, Kok Lian, Alitheen, Noorjahan Banu Mohamed, Tan, Wen Siang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509718/
https://www.ncbi.nlm.nih.gov/pubmed/28706267
http://dx.doi.org/10.1038/s41598-017-05525-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509718/
https://www.ncbi.nlm.nih.gov/pubmed/28706267
http://dx.doi.org/10.1038/s41598-017-05525-4

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