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Inhibition of the CRF(1) receptor influences the activity of antidepressant drugs in the forced swim test in rats
Hyperactivity of the hypothalamic-pituitary-adrenal axis (HPA) and impairment of the central corticotropin-releasing factor (CRF) system are factors in the pathogenesis of depression. Though several antagonists of the CRF(1) receptor were effective in the recognized behavioral tests for antidepressa...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509780/ https://www.ncbi.nlm.nih.gov/pubmed/28429110 http://dx.doi.org/10.1007/s00210-017-1377-0 |