The effect of the lamin A and its mutants on nuclear structure, cell proliferation, protein stability, and mobility in embryonic cells

LMNA gene encodes for nuclear intermediate filament proteins lamin A/C. Mutations in this gene lead to a spectrum of genetic disorders, collectively referred to as laminopathies. Lamin A/C are widely expressed in most differentiated somatic cells but not in early embryos and some undifferentiated ce...

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Detalles Bibliográficos
Autores principales: Piekarowicz, Katarzyna, Machowska, Magdalena, Dratkiewicz, Ewelina, Lorek, Daria, Madej-Pilarczyk, Agnieszka, Rzepecki, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509783/
https://www.ncbi.nlm.nih.gov/pubmed/27534416
http://dx.doi.org/10.1007/s00412-016-0610-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509783/
https://www.ncbi.nlm.nih.gov/pubmed/27534416
http://dx.doi.org/10.1007/s00412-016-0610-9

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