Hydrogen Sulfide Mediating both Excitatory and Inhibitory Effects in a Rat Model of Meningeal Nociception and Headache Generation

BACKGROUND/PURPOSE: Hydrogen sulfide (H(2)S) is a neuromodulator acting through nitroxyl (HNO) when it reacts with nitric oxide (NO). HNO activates transient receptor potential channels of the ankyrin type 1 (TRPA1) causing release of calcitonin gene-related peptide from primary afferents. Activatio...

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Detalles Bibliográficos
Autores principales: Teicher, Christiane, De Col, Roberto, Messlinger, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509793/
https://www.ncbi.nlm.nih.gov/pubmed/28769868
http://dx.doi.org/10.3389/fneur.2017.00336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509793/
https://www.ncbi.nlm.nih.gov/pubmed/28769868
http://dx.doi.org/10.3389/fneur.2017.00336

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