Role of the IL-1 Pathway in Dopaminergic Neurodegeneration and Decreased Voluntary Movement

Interleukin-1 (IL-1), a proinflammatory cytokine synthesized and released by activated microglia, can cause dopaminergic neurodegeneration leading to Parkinson’s disease (PD). However, it is uncertain whether IL-1 can act directly, or by exacerbating the harmful actions of other brain insults. To as...

Descripción completa

Detalles Bibliográficos
Autores principales: Stojakovic, Andrea, Paz-Filho, Gilberto, Arcos-Burgos, Mauricio, Licinio, Julio, Wong, Ma-Li, Mastronardi, Claudio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509814/
https://www.ncbi.nlm.nih.gov/pubmed/27356916
http://dx.doi.org/10.1007/s12035-016-9988-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509814/
https://www.ncbi.nlm.nih.gov/pubmed/27356916
http://dx.doi.org/10.1007/s12035-016-9988-x

Ejemplares similares