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Role of the IL-1 Pathway in Dopaminergic Neurodegeneration and Decreased Voluntary Movement
Interleukin-1 (IL-1), a proinflammatory cytokine synthesized and released by activated microglia, can cause dopaminergic neurodegeneration leading to Parkinson’s disease (PD). However, it is uncertain whether IL-1 can act directly, or by exacerbating the harmful actions of other brain insults. To as...
Autores principales: | Stojakovic, Andrea, Paz-Filho, Gilberto, Arcos-Burgos, Mauricio, Licinio, Julio, Wong, Ma-Li, Mastronardi, Claudio A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509814/ https://www.ncbi.nlm.nih.gov/pubmed/27356916 http://dx.doi.org/10.1007/s12035-016-9988-x |
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