Cargando…
Dampened activity of ryanodine receptor channels in mutant skeletal muscle lacking TRIC‐A
KEY POINTS: The role of trimeric intracellular cation (TRIC) channels is not known, although evidence suggests they may regulate ryanodine receptors (RyR) via multiple mechanisms. We therefore investigated whether Tric‐a gene knockout (KO) alters the single‐channel function of skeletal RyR (RyR1). W...
Autores principales: | El‐Ajouz, Sam, Venturi, Elisa, Witschas, Katja, Beech, Matthew, Wilson, Abigail D., Lindsay, Chris, Eberhardt, David, O'Brien, Fiona, Iida, Tsunaki, Nishi, Miyuki, Takeshima, Hiroshi, Sitsapesan, Rebecca |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509884/ https://www.ncbi.nlm.nih.gov/pubmed/28387457 http://dx.doi.org/10.1113/JP273550 |
Ejemplares similares
-
Enhanced activity of multiple TRIC‐B channels: an endoplasmic reticulum/sarcoplasmic reticulum mechanism to boost counterion currents
por: O'Brien, Fiona, et al.
Publicado: (2019) -
The biophysical properties of TRIC-A and TRIC-B and their interactions with RyR2
por: Hu, Jianshu, et al.
Publicado: (2023) -
TRIC-B channels display labile gating: evidence from the TRIC-A knockout mouse model
por: Venturi, Elisa, et al.
Publicado: (2013) -
Subconductance Gating and Voltage Sensitivity of Sarcoplasmic Reticulum K(+) Channels: A Modeling Approach
por: Matyjaszkiewicz, Antoni, et al.
Publicado: (2015) -
Preserved stem cell content and innervation profile of elderly human skeletal muscle with lifelong recreational exercise
por: Soendenbroe, Casper, et al.
Publicado: (2022)