Recruitment and positioning determine the specific role of the XPF‐ERCC1 endonuclease in interstrand crosslink repair

XPF‐ERCC1 is a structure‐specific endonuclease pivotal for several DNA repair pathways and, when mutated, can cause multiple diseases. Although the disease‐specific mutations are thought to affect different DNA repair pathways, the molecular basis for this is unknown. Here we examine the function of...

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Detalles Bibliográficos
Autores principales: Klein Douwel, Daisy, Hoogenboom, Wouter S, Boonen, Rick ACM, Knipscheer, Puck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510004/
https://www.ncbi.nlm.nih.gov/pubmed/28292785
http://dx.doi.org/10.15252/embj.201695223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510004/
https://www.ncbi.nlm.nih.gov/pubmed/28292785
http://dx.doi.org/10.15252/embj.201695223

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