Defining the noninferiority margin and analysing noninferiority: An overview

Noninferiority trials are used to assess whether the effect of a new drug is not worse than an active comparator by more than a noninferiority margin. If the difference between the new drug and the active comparator does not exceed this prespecified margin, noninferiority can be concluded. This marg...

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Detalles Bibliográficos
Autores principales: Althunian, Turki A., de Boer, Anthonius, Groenwold, Rolf H. H., Klungel, Olaf H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Clinical Trials
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510081/
https://www.ncbi.nlm.nih.gov/pubmed/28252213
http://dx.doi.org/10.1111/bcp.13280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510081/
https://www.ncbi.nlm.nih.gov/pubmed/28252213
http://dx.doi.org/10.1111/bcp.13280

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