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Specific Affinity Enrichment of Electrochemically Cleaved Peptides Based on Cu(II)-Mediated Spirolactone Tagging

[Image: see text] Specific digestion of proteins is an essential step for mass spectrometry-based proteomics, and the chemical labeling of the resulting peptides is often used for peptide enrichment or the introduction of desirable tags. Electrochemical oxidation yielding specific cleavage C-termina...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, de Vries, Marcel P., Permentier, Hjalmar P., Bischoff, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510089/
https://www.ncbi.nlm.nih.gov/pubmed/28593756
http://dx.doi.org/10.1021/acs.analchem.7b01039