BCAT1 controls metabolic reprogramming in activated human macrophages and is associated with inflammatory diseases

Branched-chain aminotransferases (BCAT) are enzymes that initiate the catabolism of branched-chain amino acids (BCAA), such as leucine, thereby providing macromolecule precursors; however, the function of BCATs in macrophages is unknown. Here we show that BCAT1 is the predominant BCAT isoform in hum...

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Detalles Bibliográficos
Autores principales: Papathanassiu, Adonia E., Ko, Jeong-Hun, Imprialou, Martha, Bagnati, Marta, Srivastava, Prashant K., Vu, Hong A., Cucchi, Danilo, McAdoo, Stephen P., Ananieva, Elitsa A., Mauro, Claudio, Behmoaras, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510229/
https://www.ncbi.nlm.nih.gov/pubmed/28699638
http://dx.doi.org/10.1038/ncomms16040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510229/
https://www.ncbi.nlm.nih.gov/pubmed/28699638
http://dx.doi.org/10.1038/ncomms16040

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