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Coinjection of IL2 DNA enhances E7-specific antitumor immunity elicited by intravaginal therapeutic HPV DNA vaccination with electroporation

The generation and use of therapeutic human papillomavirus (HPV) DNA vaccines represent an appealing treatment method against HPV-associated cervical cancer due to their safety and durability. Previously, we created a therapeutic HPV DNA vaccine candidate by linking the HPV16-E7 DNA sequence to calr...

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Detalles Bibliográficos
Autores principales: Sun, Yunyan, Peng, Shiwen, Yang, Andrew, Farmer, Emily, Wu, T.-C., Hung, Chien-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510480/
https://www.ncbi.nlm.nih.gov/pubmed/28492521
http://dx.doi.org/10.1038/gt.2017.38