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Toxicity and Apoptosis Related Effects of Benzimidazo [3,2-α] Quinolinium Salts Upon Human Lymphoma Cells

OBJECTIVES: The present study evaluates novel cationic quinoline derivatives known as benzimidazo[3,2-a]quinolinium salts (BQS) named NBQ-48 and ABQ-48 that have structural similarities to known anti-cancer substances such as ellipticine and berberine. METHODS: Toledo human lymphoma (ATCC CRL2631) c...

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Detalles Bibliográficos
Autores principales: Vélez, Christian, Soto, Jessica, Ríos, Karoline, Silva, Luz, Hernandez, Wigberto, Rivera, Luis A., Ortiz-Colón, Ana I., Cox, Osvaldo, Zayas, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510565/
https://www.ncbi.nlm.nih.gov/pubmed/28761559
http://dx.doi.org/10.2174/1874104501711010054