Tumor Necrosis Factor dynamically regulates the mRNA stabilome in rheumatoid arthritis fibroblast-like synoviocytes

During rheumatoid arthritis (RA), Tumor Necrosis Factor (TNF) activates fibroblast-like synoviocytes (FLS) inducing in a temporal order a constellation of genes, which perpetuate synovial inflammation. Although the molecular mechanisms regulating TNF-induced transcription are well characterized, lit...

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Detalles Bibliográficos
Autores principales: Loupasakis, Konstantinos, Kuo, David, Sokhi, Upneet K., Sohn, Christopher, Syracuse, Bethany, Giannopoulou, Eugenia G., Park, Sung Ho, Kang, Hyelim, Rätsch, Gunnar, Ivashkiv, Lionel B., Kalliolias, George D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510804/
https://www.ncbi.nlm.nih.gov/pubmed/28708839
http://dx.doi.org/10.1371/journal.pone.0179762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510804/
https://www.ncbi.nlm.nih.gov/pubmed/28708839
http://dx.doi.org/10.1371/journal.pone.0179762

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