Pioglitazone ameliorates glomerular NLRP3 inflammasome activation in apolipoprotein E knockout mice with diabetes mellitus

OBJECTIVE: The NLRP3 inflammasome plays an important role in the pathogenesis of inflammation in diabetic nephropathy (DN). Pioglitazone (PIO) has been found to exert an anti-inflammatory effect in patients with diabetes mellitus, but it is still unclear whether PIO exhibits a similar effect in DN....

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Detalles Bibliográficos
Autores principales: Wang, Yao, Yu, Bo, Wang, Li, Yang, Ming, Xia, Zhiyin, Wei, Wei, Zhang, Fengyu, Yuan, Xiaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510862/
https://www.ncbi.nlm.nih.gov/pubmed/28708885
http://dx.doi.org/10.1371/journal.pone.0181248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510862/
https://www.ncbi.nlm.nih.gov/pubmed/28708885
http://dx.doi.org/10.1371/journal.pone.0181248

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