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Lineage-dependent differences in the disease progression of Zika virus infection in type-I interferon receptor knockout (A129) mice

Zika virus (ZIKV) falls into two lineages: African (ZIKV(AF)) and Asian (ZIKV(AS)). These lineages have not been tested comprehensively in parallel for disease progression using an animal model system. Here, using the established type-I interferon receptor knockout (A129) mouse model, it is first de...

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Detalles Bibliográficos
Autores principales: Dowall, Stuart D., Graham, Victoria A., Rayner, Emma, Hunter, Laura, Atkinson, Barry, Pearson, Geoff, Dennis, Mike, Hewson, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510909/
https://www.ncbi.nlm.nih.gov/pubmed/28672028
http://dx.doi.org/10.1371/journal.pntd.0005704