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Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum

Inflammasome is an intracellular protein complex that serves as cytosolic pattern recognition receptor (PRR) to engage with pathogens and to process cytokines of the interleukin-1 (IL-1) family into bioactive molecules. It has been established that interleukin-1β (IL-1β) is important to host defense...

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Detalles Bibliográficos
Autores principales: Chang, Tzu-Hsuan, Huang, Juin-Hua, Lin, Hsiu-Chao, Chen, Wen-Yu, Lee, Yu-Hsiang, Hsu, Li-Chung, Netea, Mihai G., Ting, Jenny P.-Y., Wu-Hsieh, Betty A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510910/
https://www.ncbi.nlm.nih.gov/pubmed/28671985
http://dx.doi.org/10.1371/journal.ppat.1006485