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A novel twelve class fluctuation test reveals higher than expected mutation rates for influenza A viruses
Influenza virus’ low replicative fidelity contributes to its capacity for rapid evolution. Clonal sequencing and fluctuation tests have suggested that the influenza virus mutation rate is 2.7 × 10(–6) - 3.0 × 10(–5) substitutions per nucleotide per strand copied (s/n/r). However, sequencing assays a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511008/ https://www.ncbi.nlm.nih.gov/pubmed/28598328 http://dx.doi.org/10.7554/eLife.26437 |