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Alteration of the irisin–brain-derived neurotrophic factor axis contributes to disturbance of mood in COPD patients
COPD is accompanied by limited physical activity, worse quality of life, and increased prevalence of depression. A possible link between COPD and depression may be irisin, a myokine, expression of which in the skeletal muscle and brain positively correlates with physical activity. Irisin enhances th...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511021/ https://www.ncbi.nlm.nih.gov/pubmed/28744117 http://dx.doi.org/10.2147/COPD.S135701 |