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TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors

Understanding the processes that govern liver progenitor cell differentiation has important implications for the design of strategies targeting chronic liver diseases, whereby regeneration of liver tissue is critical. Although DNA methylation (5mC) and hydroxymethylation (5hmC) are highly dynamic du...

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Detalles Bibliográficos
Autores principales: Ancey, Pierre-Benoit, Ecsedi, Szilvia, Lambert, Marie-Pierre, Talukdar, Fazlur Rahman, Cros, Marie-Pierre, Glaise, Denise, Narvaez, Diana Maria, Chauvet, Veronique, Herceg, Zdenko, Corlu, Anne, Hernandez-Vargas, Hector
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511103/
https://www.ncbi.nlm.nih.gov/pubmed/28648900
http://dx.doi.org/10.1016/j.stemcr.2017.05.023