Nuclear Factor Erythroid 2 Regulates Human HSC Self-Renewal and T Cell Differentiation by Preventing NOTCH1 Activation

Nuclear factor erythroid-derived 2 (NF-E2) has been associated with megakaryocyte maturation and platelet production. Recently, an increased in NF-E2 activity has been implicated in myeloproliferative neoplasms. Here, we investigate the role of NF-E2 in normal human hematopoiesis. Knockdown of NF-E2...

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Detalles Bibliográficos
Autores principales: Di Tullio, Alessandro, Passaro, Diana, Rouault-Pierre, Kevin, Purewal, Sukhveer, Bonnet, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511106/
https://www.ncbi.nlm.nih.gov/pubmed/28648895
http://dx.doi.org/10.1016/j.stemcr.2017.05.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511106/
https://www.ncbi.nlm.nih.gov/pubmed/28648895
http://dx.doi.org/10.1016/j.stemcr.2017.05.027

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